(-)-Arctiin
| Overview | |
| Catalog # | bs-75277C |
| Product Name | (-)-Arctiin |
| Specifications | |
| Storage Buffer | Crystals |
| Storage Condition | Stable for 2 years after receipt when stored at -20°C. |
| Target | |
| Product Information | CAS Number: 20362-31-6 Molecular formula: C27H34O11 Molecular weight: 534.6 Purity: >99% (HPLC) Appearance: Colorless crystals. Solubility: Soluble in DMSO (20mg/ml), DMF (20mg/ml) or ethanol (1mg/ml). Insoluble in water. InChiKey: XOJVHLIYNSOZOO-SWOBOCGESA-N SMILES: O=C1OC[C@H](CC2=CC(OC)=C(OC)C=C2)[C@H]1CC3=CC(OC)=C(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O4)C=C3 |
| Description | Metabolizes into (-)-Arctigenin (AG-CN2-0530). Multifunctional natural compound with photoprotective, anti-inflammatory, antidiabetic, antiproliferative and antiviral activities. Decreasing the production of nitric oxide and pro-inflammatory cytokines, such as IL-1beta, IL-6, TNF-alpha and PGE2 through the inhibition of PI3K/AKT/NF-kappaB signaling pathway. Suppresses cyclin D1 protein expression in multiple types of human tumor cells. Inhibitor of HIV-I integrase. Inhibits adipogenesis in 3T3-L1 adipocytes through the inhibition of PPARgamma and C/EBPalpha and the activation of AMPK signaling pathways. Photoprotective agent showing UVB protection in keratinocytes, which is mediated by miRNA responses and the suppression of UVB-induced cell death. Inhibitor of STAT3 phosphorylation at tyrosine 705 residue. |
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